Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release
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چکیده
منابع مشابه
Protective Role of Apigenin Against Aβ 25-35 Toxicity Via Inhibition of Mitochondrial Cytochrome c Release
Introduction: Cognitive dysfunction is the most common problem of patients with Alzheimer disease (AD). The pathological mechanism of cognitive impairment in AD may contribute to neuronal loss, synaptic dysfunction, and alteration in neurotransmitters receptors. Mitochondrial synapses dysfunction due to the accumulation of amyloid beta (Aβ) is one of the earliest pathological features of AD. Th...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2011
ISSN: 1001-0602,1748-7838
DOI: 10.1038/cr.2011.82